Tag Archives: nanotechnology

UCLA researchers design nanomachine that kills cancer cells

cancer cells Well, as long as I’m posting about nanotechnology, check this out (Via PhysOrg):

Researchers from the Nano Machine Center at the California NanoSystems Institute at UCLA have developed a novel type of nanomachine that can capture and store anticancer drugs inside tiny pores and release them into cancer cells in response to light. Known as a “nanoimpeller,” the device is the first light-powered nanomachine that operates inside a living cell, a development that has strong implications for cancer treatment.

The study was conducted jointly by Jeffrey Zink, UCLA professor of chemistry and biochemistry, and Fuyu Tamanoi, UCLA professor of microbiology, immunology and molecular genetics. A little further along in the press release:

The pores of the particles can be loaded with cargo molecules, such as dyes or anticancer drugs. In response to light exposure, a wagging motion occurs, causing the cargo molecules to escape from the pores and attack the cell. Confocal microscopic images showed that the impeller operation can be regulated precisely by the intensity of the light, the excitation time and the specific wavelength.

The cells they killed were only in vitro, of course, and there’s the usual caveat:

Tamanoi and Zink say the research represents an exciting first step in developing nanomachines for cancer therapy and that further steps are required to demonstrate actual inhibition of tumor growth.

The accomplishment is detailed in the nanotechnology journal Small. You can find the citation here, but you’ll have to pay to read the article.

And look out for the fine print. One would think that in a nanotechnology journal, it might be very fine indeed.

(Image: Wikimedia Commons.)

[tags]nanotechnology, cancer, medicine, nanomachines[/tags]

It’s not molecular manufacturing, but you can see it from here:

Vacuum chamber of scanning tunneling electron microscope A new $15 million research project is being launched to enable manufacturing at the almost unimaginably small scale of one atom at a time. (Via Responsible Nanotechnology.)

The technology is based on the established ability to remove individual hydrogen atoms from a silicon surface using a scanning tunneling microscope, and could enable a wide variety of devices and products, including:

* Ultra-low-power semiconductors for cellphones and other wireless communications.
* Sensors with ultra-high sensitivity.
* Data encryption orders of magnitude more secure than existing technology.
* Optical elements that enable unprecedented performance in computing and communications.
* Customized surfaces that would have an array of applications in the biomedical and pharmaceutical industries.
* Nanoscale genomics arrays that would enable a person’s complete genetic sequence to be read in less than two hours.

The Atomically Precise Manufacturing Consortium is being led by Zyvex Labs LLC, a molecular nanotechnology company based in Richardson, Texas. The project includes a mixture of funding from the Defense Advanced Research Projects Agency, the Texas Emerging Technology Fund and cost sharing from the team members.

As Mike Treder at the Responsible Nanotechnology blog notes:

This is still not quite equivalent to molecular manufacturing, but it does represent a major step along the way. And make no mistake, that is the eventual goal of this team.

(Image: Kristian Molhave, via Wikimedia Commons.)

[tags]nanotechnology, molecular manufacturing, technology[/tags]

A Chemical Brain To Control Nanobots

A brain to control all those tiny machines rebuilding your bodyNanotechnology is perhaps the most rapidly advancing new technology out there right now. All kinds of nanomachines based on biochemical mechanisms, tiny structures of metal or other techniques are being created and studied in universities and laboratories around the world.

Scientists have now created a device two billionths of a metre in size that could work as a chemical ‘brain’ for a group of nanomachines. Potentially this could lead to their use in medical techniques such as nano-surgery on tumours.

“If [in the future] you want to remotely operate on a tumour you might want to send some molecular machines there,” explained Dr Anirban Bandyopadhyay of the International Center for Young Scientists, Tsukuba, Japan. “But you cannot just put them into the blood and [expect them] to go to the right place.”

Dr Bandyopadhyay believes his device may offer a solution. One day they may be able to guide the nanobots through the body and control their functions, he said.

“That kind of device simply did not exist; this is the first time we have created a nano-brain,” he told BBC News.

[story and image via BBC Science/Nature. Thanks to Kian Momtahan for the link!]

Carbon nanotube radio fits on the head of a pin

Oh, carbon nanotubes, is there anything you can’t do?  Researchers at the University of Illinois Urbana-Champaign have come up with a radio, all of whose reception components are made of carbon nanotubes.  This is pretty much just a proof-of-concept, no one’s going to be mass-producing nano-radios anytime soon, and the actual amplifier and headphone jack can’t really be scaled down, limiting the lower size limit. 

What it does show is that nanotubes can be grown in arranged structures and the conductive properties are good enough that they may be a suitable replacement for silicon.  This is good news for solar manufacturers worried about a silicon shortage.  Not to mention it’d help with that pesky ewaste problem.  Listen to an interview with one of the researchers here.

(via Science Friday) (photo from flickr user jschneid)

Centre for Responsible Nanotechnology at five years old

This Tetrahedron was constructed from DNA molecules by Andrew Turberfield at the University of OxfordVia the blog Responsible Nanotechnology, Mike Treder, Executive Director of the Centre for Responsible Nanotechnology presents his thoughts on the state of the emerging science of nanotech, five year’s since the centre’s creation. He begins by highlighting the original positions made by CRN in 2003:

“Early in 2003, we published the following foundational statements that summarized CRN’s basic positions:

The following post then analyses each of these in turn, comparing things now in 2008 to how it was then back in 2003. There’s been a lot of progress in the field since then but they believe their assumptions remain true. As new ways to manipulate matter at the nanoscale are discovered, potential beneficial uses and dangers will increase exponentially. Theodore Judson’s forthcoming novel ‘The Martian General’s Daughter’ for instance, has a Roman-like empire collapsing because a nanotechnology plague is destroying the metal inside computers and equipment.

[DNA tetrahedron created by Andrew J. Turberfield, Department of Physics, University of Oxford. Image via Nanorex, Inc.]