Tag Archives: genetics

The auroch revival: bringing back the big beef

It’s not often that we get to hear about people working on a scientific project previously instigated by Hitler and the Nazi Party of Germany… though this is thankfully a far more benign application of eugenic theory than the atrocities of the Second World War. Italian scientists are trying to recreate the auroch, an extinct breed of European mega-cattle, by selective “back breeding” and genetic analysis [via SlashDot; image courtesy Wikimedia Commons]:

“We were able to analyse auroch DNA from preserved bone material and create a rough map of its genome that should allow us to breed animals nearly identical to aurochs,” said team leader Donato Matassino, head of the Consortium for Experimental Biotechnology in Benevento, in the southern Campania region.

“We’ve already made our first round of crosses between three breeds native to Britain, Spain and Italy. Now we just have to wait and see how the calves turn out.”

The last animal disappeared from the British Isles in the Iron Age and the breed was declared extinct in 1627 after a female died in the forests of Poland.

Aurochs are depicted in ochre and charcoal in paintings found on the walls of cave galleries such as those at Lascaux in France and Altamira in Spain. Caesar described them in The Gallic Wars as being “a little below the elephant in size” and a favourite hunting prey for wild Germanic tribesmen.

Their abiding mystique means they remain as the symbol of several states and cities in Europe, having figured prominently in Teutonic folklore. In ancient times, killing an auroch was seen as a great demonstration of courage, with the horns turned into silver-clad drinking cups.

Exactly why we need to recreate a breed of cows with the size and temperament of a rhinocerous isn’t abundantly clear, and some researchers suggest that the back-breeding process will produce animals that, while they may look the part, are inevitably very different from the original aurochs at a genetic level. But then it probably won’t be more than a decade or so before we can reliably clone animals from archived DNA samples, Jurassic Park style.

Perhaps retro-engineered auroch hunting will become the European equivalent of the rich man’s African safari holiday? I’d be right behind that idea, on the proviso that the would-be hunters were obliged to use the weapons of the Middle Ages in their attempts to bag a trophy… 😉

The scent of dead stardom – Eau de Jacko

Michael Jackson statueAh, December – time to crank out the ‘silly season’ media stories to fill the gaps in between the “best of the decade” posts. So here’s a way-out weird  news article for you: an LA-based company called My DNA Fragrance (there’s a clue in the name) has joined forces with a collector of celebrity hair and started making perfumes based on DNA extracted from snippets of the barnets of superstars. [via The Daily Swarm; image by Sjors Provoost]

No, apparently this is a true story. But I hope you’ll excuse me the levity of slicing a quote from the coverage and using it out of context (purely for the lulz, you understand):

“The biggest seller is Elvis, but MJ is selling very well too. It’s a powerful fragrance and there is no alcohol in it.

Oh, the irony. 🙂

We’ll leave aside the speculations about our bizarre obsession with celebrity (after all, is this so different from touching relics of the saints and other such Medieval behaviours?), and leap instead straight to the copyright problem. What happens if my hair is harvested without my knowledge, while I’m treading the red carpet somewhere*? Don’t I or my descendants have a right to the profit from perfume based on my DNA? How many changes would need to be made to a DNA string to make it legally ‘different’ to the originating source?

And most importantly, what the hell does Eau de Michael Jackson smell like?

[ * Hey, this is a speculative website, okay? ]

Beginner’s guide to DNA sequencing

Model DNA moleculeGenetic engineering and DNA sequencing are regular features in our news posts here at Futurismic, and in many other venues much less explicitly future-focussed. The technology of life’s tiny building blocks is steadily becoming ubiquitous – hell, you can even buy a DNA synthesizer on eBay [via Paul McAuley] – but it’s still a pretty hardcore scientific discipline, one that takes years of study and research to fully understand.

Luckily for us curious laypersons, Ars Technica is running a series of articles aiming to explain the basics of genetic science in terms that we should be able to grasp – though a basic high-school level understanding of science is probably still a prerequisite to get the best out of it. The first instalment is all about the basic principles of DNA sequencing – the underlying ideas that the latest and greatest methods are built upon. Some of the diagrams and chemical names might be a bit intimidating, but it’s a well-written piece and worth persisting with if you’re genuinely curious about how it all works. [image by net_efekt]

A spoonful of friendly bacteria helps the medicine go down

pillsGenetically engineered bacteria have been used to deliver therapies for bowel disorders like inflammatory bowel disease:

The bacterium is able to deliver the protein, a human growth factor called KGF-2, directly to the damaged cells that line the gut, unlike other treatments which can cause unwanted side effects. Also unlike other treatments, it is envisaged that patients will be able to control the medication themselves by ingesting xylan, perhaps in the form of a drink.

I am not 1 of the 400 Britons who suffers from IBD but it is wonderful to see that genetic engineering has such excellent medical applications.

[from Science Daily][image from Deco Fernandez on flickr]

Consumer DNA screening is here; what happens next?

digital rendering of DNAI’ve recommended Jan Chipchase’s Future Perfect blog before as a great source for near-future speculation with a street-level twist, and it looks like it’s time I did so again. Chipchase has just purchased one of the $99 DNA testing kits from 23andme, inspiring the following thoughts:

With an increasing number of medical and judicial proceedings pulling on DNA data and a continious trickle of whose-the-father paternity testing DNA is slowly but surely moving mainstream. Who’ll be the first to take individual’s DNA data and mash it up with dating profiles? Nature versus nurture? Bring on the hucksters.

The rise in adoption/use of DNA is particularly interesting because it affects people, families deeply and retrospectively. Your dad for the last 40 years? He’s not, y’know. (For source stats head over to Measuring paternal discrepancy and its public health consequences by Mark A Bellis et al. – they cite ~0.8% to 30% paternal discrepancy, median 3.7%)

Roll forward 20 years when you can obtain a DNA test for the cost of a packet of gum – hell, it might even come in the form of a stick of ‘DNA Brand’ gum where the consumer is encouraged to spit out and stick after use.

Can you think of any Gibsonian street uses for ubiquitous affordable DNA testing? [image by ynse]